SHEDDING POUNDS, EASING PAIN: HOW WEIGHT LOSS MEDICATIONS ARE TACKLING INFLAMMATION AND CHRONIC CONDITIONS

Glucagon-like peptide 1, also known as GLP-1, was first discovered in 1981 isolated from the pancreatic islet of anglerfish. Through further research, scientists found that it enhances insulin secretion in response to nutrient ingestion. Originally studied as a potential treatment for type 2 diabetes, GLP-1 medications are now also recognized for their weight loss benefits. Recent studies are showing that GLP-1 medications not only help with weight management but also have significant anti-inflammatory effects, benefiting individuals with chronic autoimmune conditions. In some cases, these medications may even help put certain conditions into remission.

THE LINK BETWEEN OBESITY AND CHRONIC CONDITIONS

The Impact of Excess Weight on Health:

Carrying excess weight significantly impacts health by increasing the risk of developing several chronic diseases including heart disease, type 2 diabetes, high blood pressure, stroke, sleep apnea, osteoarthritis, and even mental health conditions like depression and anxiety.

Chronic inflammation and Its Role in Pain and Disease:

Obesity causes inflammation because excess fat tissue releases cytokines, proteins that trigger inflammation. This is the type of inflammation that leads to metabolic complications and can lead to conditions such as those mentioned above. If chronic inflammation is left unaddressed, it causes damage to healthy cells leading to tissue death and damage to the DNA in previously healthy cells.

Lifestyle Factors:

Several lifestyle factors can contribute to chronic inflammation. Some common contributors include:

A diet high in sugar, refined carbs, and processed foods
Drinking alcohol in excess or smoking cigarettes
Obesity
Chronic stress
Irregular sleep patterns

HOW WEIGHT LOSS MEDICATIONS WORK BEYOND THE SCALE

GLP-1 Medications and Their Mechanisms:

Glucagon-like peptide – 1 (GLP-1) medications mimic the action of the natural hormone GLP-1 in the body, which is released from the gut after eating. The hormone helps control blood sugar by enhancing insulin release (which lowers sugar levels) and reducing glucagon (which raises sugar levels). Additionally, GLP-1 also slows down gastric emptying stomach and helps you to feel fuller longer. These two actions contribute to weight loss and improved blood sugar regulation.

How GLP-1’s reduce inflammation:

GLP-1 medications reduce inflammation and balance the body’s metabolism by influencing key pathways in the body. This includes regulating immune response, improving blood sugar regulation, optimizing fat metabolism, and reducing oxidative stress – all of which contribute to lower levels of systemic inflammation.

Reducing Inflammation Through Weight Loss:

When you lose weight, the production of inflammatory chemicals decreases. Reducing body fat helps lower inflammation, which in turn reduces the risk of developing chronic conditions associated with excess weight.

HOW WEIGHT LOSS MEDICATIONS CAN IMPROVE SPECIFIC CHRONIC CONDITIONS

Arthritis and Joint Pain:

Losing weight reduces pressure on joints, which lessens wear and tear on cartilage. Lowering systemic inflammation reduces pain and swelling in the areas affected by arthritis and joint pain.

Type 2 Diabetes and Insulin Resistance:

GLP-1 medications stimulate the pancreas to release more insulin and suppresses glucagon, resulting in improved blood sugar control. Additionally, these medications promote satiety and delay gastric emptying which can lead to weight loss. Together, these effects help improve metabolic health and are beneficial in managing type 2 diabetes and insulin resistance.

Heart Disease and Cardiovascular Health:

GLP-1’s decrease inflammation, a major contributor to cardiovascular disease. Studies have shown that GLP-1 medications can improve blood flow, lower blood pressure, and promote better circulation, all of which contribute to improved cardiovascular health.

A HOLISTIC APPROACH TO MANAGING CHRONIC CONDITIONS

The Role of Lifestyle Changes:

There are many ways to address factors that may be contributing to chronic inflammation.

Stress Management – While encountering stress is inevitable, implementing a daily routine that helps you to wind down and de-stress before/after your day can be very beneficial for mental well-being. Additionally, daily movement such as weightlifting, walking, or yoga can help clear your mind. Many also find journalling helpful for stress management.
Book a massage – massages promote relaxation and have been shown to reduce inflammation and aid in pain relief.
Limit alcohol intake – Excessive alcohol consumption contributes to increased inflammation. Reducing intake may help prevent chronic inflammation.
Eat a balanced diet – Focus on eating nutrient dense whole foods that will fuel your body for success. Proper nutrition plays a key role in maintaining overall health.

Collaborating with Healthcare Providers:

If you are considering beginning a weight loss/wellness journey and with GLP-1 medications, it is important to consult with a trusted healthcare provider. At Premier Weight Loss, we are committed to joining you on your journey and helping you achieve your health goals through personalized care and guidance.

CONCLUSION:

In conclusion, GLP-1 medications offer more than just weight loss support – they provide a wide range of health benefits that can enhance overall well-being. Whether you are looking to lose weight, improve metabolic health, or decrease inflammation, GLP-1 medications can be a valuable tool in your wellness journey. Always work with a healthcare provider to determine if GLP-1 medications are right for you and remember that combining medication with healthy lifestyle changes will lead to the best long-term results.